Peptide Arcana
Ecallantide: Blocks plasma kallikrein, the enzyme that frees bradykinin, which makes vessels leak. Stops attacks of hereditary angioedema.

Ecallantide

FDA approvedSkin and aging

How it works

Blocks plasma kallikrein, the enzyme that frees bradykinin, which makes vessels leak. Stops attacks of hereditary angioedema.

What it's made of

A small protein of 60 amino acids: Kunitz domain 1 of TFPI, a human protein that slows clotting, with 7 changes so it blocks kallikrein. It is made in yeast.

What it's for

Prescribed for
Acute attacks of hereditary angioedema, from age 12.
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Educational satire, not medical advice.